A multi-disciplinary research program is used to identify solutions to neurological and respiratory disorders. Our research combines biomedical, drug discovery, and clinical sciences to better understand and treat diseases.
Identification of new therapeutics requires high-throughput screening of genes and chemical library. We use the phenotypic-based drug and gene screening in zebrafish and cell-based assays to identify new drug compounds for the treatment of neurological and respiratory disorders.
To better understand the pathophysiology underlying breathing disorders, we perform clinical studies in patient populations. Using polysomnography and brain imaging, we look at the electrocortical signatures associated with breathing disorders such as opioid-induced respiratory depression.