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Brain & Breathing

Biomedical Platform

We explore the neural control of breathing using state-of-the-art neuroscience and physiology tools. Our platform combines optogenetics, neurophysiology, pharmacology, transgenics, neuro-imaging to better understand the neural networks regulating breathing.

Drug and Gene Discovery Platform

Identification of new therapeutics requires high-throughput screening of genes and chemical library. We use the phenotypic-based drug and gene screening in zebrafish and cell-based assays to identify new drug compounds for the treatment of neurological and respiratory disorders.

Clinical Platform

To better understand the pathophysiology underlying breathing disorders, we perform clinical studies in patient populations. Using polysomnography and brain imaging, we look at the electrocortical signatures associated with breathing disorders such as opioid-induced respiratory depression.